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Clinical Trials


Alzheimer's Disease


○ Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug.

○ Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients.

○ Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report.

○ Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation.

○ Effects of cannabidiol (CBD) on regional cerebral blood flow

○ The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors.

○ The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system.

○ Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.

○ A Systematic Review of Plant-Derived Natural Compounds for Anxiety Disorders.

○ The Endocannabinoid System and Anxiety.

○ Cannabidiol regulation of emotion and emotional memory processing: relevance for treating anxiety-related and substance abuse disorders.

○ Effect of prior foot shock stress and Δ9-tetrahydrocannabinol, cannabidiolic acid, and cannabidiol on anxiety-like responding in the light-dark emergence test in rats.

○ Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report.

○ Cannabidiol Does Not Dampen Responses to Emotional Stimuli in Healthy Adults.



○ Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress.

○ The endocannabinoid system: an emerging key player in inflammation.

○ Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice.

○ Cannabinoids, endocannabinoids, and related analogs in inflammation.

○ Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: role for the adenosine A(2A) receptor.

○ Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors.

○ Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis.

○ Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation.

○ Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement.

○ Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption.

○ Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation.

○ Cannabidiol attenuates cisplatin-induced nephrotoxicity by decreasing oxidative/nitrosative stress, inflammation, and cell death.

○ Cannabinoids in clinical practice.

○ Cannabinoids, inflammation, and fibrosis.

○ Endocannabinoid 2-arachidonoylglycerol protects inflammatory insults from sulfur dioxide inhalation via cannabinoid receptors in the brain.

○ Protective effect of cannabidiol on hydrogen peroxide‑induced apoptosis, inflammation and oxidative stress in nucleus pulposus cells.

○ Mechanisms of action of cannabidiol in adoptively transferred experimental autoimmune encephalomyelitis.



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